J Pediatr Neurol 2019; 17(06): 223
DOI: 10.1055/s-0038-1677501
Letter to the Editor
Georg Thieme Verlag KG Stuttgart · New York

Infantile Acquired Vitamin B12 Deficiency

Sora Yasri
1  KMT Primary Care Center, Bangkok, Thailand
Viroj Wiwanitkit
2  Department of Community Medicine, Dr. D.Y. Patil University, Pune, Maharashtra, India
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30. Oktober 2018

12. Dezember 2018

26. Januar 2019 (online)

Reply to “Infantile Acquired Vitamin B12 Deficiency”

We read the article on “Acquired Vitamin B12 Deficiency in Infancy” with a great interest.[1] Fadilah et al concluded that “We recommend early detection by screening in infants with suggestive clinical presentations, using urine methylmalonic acid/plasma homocysteine as screening tools, maternal screening during pregnancy, and long-term neurodevelopmental follow-up.”[1] We would like to share ideas on this topic.

First, vitamin B12 deficiency is usually seen in the areas where the local people have strict vegetarianism. In endemic area of vitamin B12 deficiency, the screening test might be useful in detection of the deficient mother. However, this might be expected. Whether the universal vitamin B12 supplementation to the mother is more useful approach should be discussed. In our setting, Indochina, the supplementation is uncommon in Cambodia and the problem of vitamin B12 deficiency in mother and infant is reported.[2] It is the recommendation for this setting that the maternal vitamin B12 supplementation is raised.[2] [3]