Semin Neurol 2019; 39(01): 061-072
DOI: 10.1055/s-0038-1676992
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Acute Stroke

Andrea Morotti
1  Stroke Unit, IRCCS Mondino Foundation, Pavia, Italy
Loris Poli
2  Dipartimento di Scienze Mediche e Chirurgiche, Clinica Neurologica, Università degli Studi di Brescia, Brescia, Italia
Paolo Costa
3  U.O. di Neurologia, Istituto Clinico Fondazione Poliambulanza, Brescia, Italy
› Author Affiliations
Funding None
Further Information

Publication History

Publication Date:
11 February 2019 (online)


Stroke remains one of the leading determinants of death and severe disability worldwide. It is a medical emergency with a narrow window for recognition and administration of outcome-modifying treatment in the emergency department. Ischemic stroke accounts for the majority of cerebrovascular events and revascularization therapies such as intravenous thrombolysis and endovascular thrombectomy are the mainstays of treatment in carefully selected patients. Intracerebral hemorrhage is less common but remains the deadliest type of stroke. Blood pressure reduction and hemostatic treatment in case of coagulopathy are the cornerstones of acute intracerebral hemorrhage treatment. Admission to dedicated stroke units is associated with improved outcome in patients suffering from acute stroke.


Andrea Morotti, Loris Poli, and Paolo Costa report no disclosures.