Journal of Pediatric Epilepsy 2018; 07(03): 103-105
DOI: 10.1055/s-0038-1676858
Review Article
Georg Thieme Verlag KG Stuttgart · New York

Dravet Syndrome and Psychiatric Comorbidity

W. Boudewijn Gunning
1  Stichting Epilepsie Instellingen Nederland, Zwolle, The Netherlands
Lisette J.J.M. van Gemert
2  Epilepsy Center Kempenhaeghe, Heeze, The Netherlands
› Author Affiliations
Further Information

Publication History

12 May 2018

19 November 2018

Publication Date:
20 December 2018 (online)


This is a review of the prevalence of psychiatric comorbidity in patients with Dravet syndrome (DS) and the predictors of psychiatric comorbidity. Symptoms of attention-deficit hyperactivity disorder are most frequently reported in children with DS. Autistic features and “other behavior problems” are also found in a considerable proportion of children. No consistent relationship has been found with intellectual disability level, age of onset of seizures, delay in diagnosis, and seizure frequency. A major limitation of the literature is that formal psychiatric assessment has rarely been applied.