Clin Colon Rectal Surg 2019; 32(02): 134-137
DOI: 10.1055/s-0038-1676479
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Applying Enhanced Recovery Pathways to Unique Patient Populations

Grace C. Lee
1   Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts
,
Richard A. Hodin
1   Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts
› Author Affiliations
Further Information

Publication History

Publication Date:
28 February 2019 (online)

Abstract

Enhanced Recovery after Surgery (ERAS) pathways have become popular in colorectal surgery due to their associated decrease in length of stay (LOS), complications, and readmission rate. However, it is unclear if these pathways are safe, feasible, or effective in unique patient populations such as elderly patients, urgent/emergent surgeries, patients with specific comorbidities, inflammatory bowel disease, or pediatric patients. Enhanced recovery pathways appear safe in elderly patients, associated with decreased complications, though with slightly lower rates of adherence and increased LOS and readmission rates. Modified ERAS pathways have been applied to urgent and emergent surgeries, resulting in decreased morbidity and LOS. There have been no studies that performed subgroup analyses of ERAS pathways in patients with specific comorbidities. Studies investigating patients with inflammatory bowel disease on enhanced recovery pathways are extremely limited, but suggest that they are safe and feasible. Data on ERAS pathways in pediatric patients are still emerging. Therefore, though data are sparse, enhanced recovery pathways appear to be safe in unique patient populations, with similar efficacy in decreasing LOS and complications. There is an urgent need for more studies investigating these specific patient groups to aid perioperative decision making by colorectal surgeons.

 
  • References

  • 1 Ljungqvist O, Scott M, Fearon KC. Enhanced Recovery After Surgery: a review. JAMA Surg 2017; 152 (03) 292-298
  • 2 Varadhan KK, Neal KR, Dejong CH, Fearon KC, Ljungqvist O, Lobo DN. The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a meta-analysis of randomized controlled trials. Clin Nutr 2010; 29 (04) 434-440
  • 3 Greco M, Capretti G, Beretta L, Gemma M, Pecorelli N, Braga M. Enhanced recovery program in colorectal surgery: a meta-analysis of randomized controlled trials. World J Surg 2014; 38 (06) 1531-1541
  • 4 Gustafsson UO, Hausel J, Thorell A, Ljungqvist O, Soop M, Nygren J. ; Enhanced Recovery After Surgery Study Group. Adherence to the enhanced recovery after surgery protocol and outcomes after colorectal cancer surgery. Arch Surg 2011; 146 (05) 571-577
  • 5 Pisarska M, Pędziwiatr M, Małczak P. , et al. Do we really need the full compliance with ERAS protocol in laparoscopic colorectal surgery? A prospective cohort study. Int J Surg 2016; 36 (Pt A): 377-382
  • 6 Keller DS, Bankwitz B, Nobel T, Delaney CP. Using frailty to predict who will fail early discharge after laparoscopic colorectal surgery with an established recovery pathway. Dis Colon Rectum 2014; 57 (03) 337-342
  • 7 Bagnall NM, Malietzis G, Kennedy RH, Athanasiou T, Faiz O, Darzi A. A systematic review of enhanced recovery care after colorectal surgery in elderly patients. Colorectal Dis 2014; 16 (12) 947-956
  • 8 Feroci F, Lenzi E, Baraghini M. , et al. Fast-track surgery in real life: how patient factors influence outcomes and compliance with an enhanced recovery clinical pathway after colorectal surgery. Surg Laparosc Endosc Percutan Tech 2013; 23 (03) 259-265
  • 9 Slieker J, Frauche P, Jurt J. , et al. Enhanced recovery ERAS for elderly: a safe and beneficial pathway in colorectal surgery. Int J Colorectal Dis 2017; 32 (02) 215-221
  • 10 Gonzalez-Ayora S, Pastor C, Guadalajara H. , et al. Enhanced recovery care after colorectal surgery in elderly patients. Compliance and outcomes of a multicenter study from the Spanish working group on ERAS. Int J Colorectal Dis 2016; 31 (09) 1625-1631
  • 11 Baek SJ, Kim SH, Kim SY, Shin JW, Kwak JM, Kim J. The safety of a “fast-track” program after laparoscopic colorectal surgery is comparable in older patients as in younger patients. Surg Endosc 2013; 27 (04) 1225-1232
  • 12 Braga M, Pecorelli N, Scatizzi M, Borghi F, Missana G, Radrizzani D. ; PeriOperative Italian Society. Enhanced recovery program in high-risk patients undergoing colorectal surgery: results from the PeriOperative Italian Society Registry. World J Surg 2017; 41 (03) 860-867
  • 13 Shida D, Tagawa K, Inada K. , et al. Modified enhanced recovery after surgery (ERAS) protocols for patients with obstructive colorectal cancer. BMC Surg 2017; 17 (01) 18
  • 14 Wisely JC, Barclay KL. Effects of an Enhanced Recovery After Surgery programme on emergency surgical patients. ANZ J Surg 2016; 86 (11) 883-888
  • 15 Moydien MR, Oodit R, Chowdhury S, Edu S, Nicol AJ, Navsaria PH. Enhanced recovery after surgery (ERAS) in penetrating abdominal trauma: a prospective single-center pilot study. S Afr J Surg 2016; 54 (04) 7-10
  • 16 Messenger DE, Curtis NJ, Jones A, Jones EL, Smart NJ, Francis NK. Factors predicting outcome from enhanced recovery programmes in laparoscopic colorectal surgery: a systematic review. Surg Endosc 2017; 31 (05) 2050-2071
  • 17 Ferrari L, Krane MK, Fichera A. Inflammatory bowel disease surgery in the biologic era. World J Gastrointest Surg 2016; 8 (05) 363-370
  • 18 Ehteshami-Afshar S, Nikfar S, Rezaie A, Abdollahi M. A systematic review and meta-analysis of the effects of infliximab on the rate of colectomy and post-operative complications in patients with inflammatory bowel disease. Arch Med Sci 2011; 7 (06) 1000-1012
  • 19 Spinelli A, Bazzi P, Sacchi M. , et al. Short-term outcomes of laparoscopy combined with enhanced recovery pathway after ileocecal resection for Crohn's disease: a case-matched analysis. J Gastrointest Surg 2013; 17 (01) 126-132 , discussion 132
  • 20 Andersen J, Kehlet H. Fast track open ileo-colic resections for Crohn's disease. Colorectal Dis 2005; 7 (04) 394-397
  • 21 Reismann M, Dingemann J, Wolters M, Laupichler B, Suempelmann R, Ure BM. Fast-track concepts in routine pediatric surgery: a prospective study in 436 infants and children. Langenbecks Arch Surg 2009; 394 (03) 529-533
  • 22 Shinnick JK, Short HL, Heiss KF, Santore MT, Blakely ML, Raval MV. Enhancing recovery in pediatric surgery: a review of the literature. J Surg Res 2016; 202 (01) 165-176
  • 23 West MA, Horwood JF, Staves S. , et al. Potential benefits of fast-track concepts in paediatric colorectal surgery. J Pediatr Surg 2013; 48 (09) 1924-1930
  • 24 Leeds IL, Boss EF, George JA, Strockbine V, Wick EC, Jelin EB. Preparing enhanced recovery after surgery for implementation in pediatric populations. J Pediatr Surg 2016; 51 (12) 2126-2129