PDF icon Download PDF
Semin Liver Dis 2019; 39(01): 104-110
DOI: 10.1055/s-0038-1676099
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Primary Sclerosing Cholangitis and Psychological Wellbeing: A Scoping Review

Veronica Ranieri
1   Research and Development Unit, Tavistock Centre, Tavistock and Portman NHS Foundation Trust, London, United Kingdom
2   Department of Science and Technology Studies, University College London, London, United Kingdom
,
Kathy McKay
1   Research and Development Unit, Tavistock Centre, Tavistock and Portman NHS Foundation Trust, London, United Kingdom
3   Institute of Psychology, Health and Society, Waterhouse Building, Block B, Brownlow Street, University of Liverpool, Liverpool, United Kingdom
,
Martine Walmsley
4   PSC Support, Didcot, United Kingdom
,
Robert Senior
1   Research and Development Unit, Tavistock Centre, Tavistock and Portman NHS Foundation Trust, London, United Kingdom
,
Douglas Thorburn
5   Sheila Sherlock Liver Centre and UCL Institute of Liver and Digestive Health, Royal Free Hospital, London, United Kingdom
,
Eilis Kennedy
1   Research and Development Unit, Tavistock Centre, Tavistock and Portman NHS Foundation Trust, London, United Kingdom
6   Research Department of Clinical, Educational & Health Psychology, University College London, London, United Kingdom
› Author Affiliations
Further Information

Publication History

Publication Date:
22 November 2018 (online)

   Permissions and Reprints
Preview

Abstract

Primary sclerosing cholangitis (PSC) is a chronic liver disease resulting from the inflammation and scarring of an individual's hepatic bile ducts. With no curative treatment available and a risk of potentially severe complications and death, it is likely that those diagnosed with the illness may experience impairments in their psychological wellbeing. The aim of this scoping review is to locate, chart, and summarize all available literature on how PSC affects mental health and psychological wellbeing, as well as the factors that may or may not impact on the psychological wellbeing of those who have this diagnosis. This exercise identified five key themes within the literature: prevalence and characteristics of mental health problems, quality of life, unmet needs, medical treatment, and biomarkers. Three key recommendations for clinical practice emerge from this review.

Keywords

primary sclerosing cholangitis - mental health - psychological wellbeing - scoping review

Supplementary Material