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Thromb Haemost 2018; 118(12): 2134-2144
DOI: 10.1055/s-0038-1675601
Blood Cells, Inflammation and Infection
Georg Thieme Verlag KG Stuttgart · New York

α1-Antichymotrypsin Present in Therapeutic C1-Inhibitor Products Competes with Selectin–Sialyl LewisX Interaction

Authors

  • Ruchira Engel*

    1   Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands
  • Laura Delvasto-Nuñez*

    1   Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands
  • Dorina Roem

    1   Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands
  • Gerard van Mierlo

    1   Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands
  • Stephanie Holst

    2   Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands
  • Agnes L. Hipgrave Ederveen

    2   Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands
  • Jaap D. van Buul

    3   Department of Molecular Cell Biology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands
  • Manfred Wuhrer

    2   Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands
  • Diana Wouters

    1   Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands
  • Sacha Zeerleder

    1   Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands
    4   Department of Hematology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    5   Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
    6   Department for BioMedical Research, University of Bern, Bern, Switzerland