CC BY-NC-ND 4.0 · Int Arch Otorhinolaryngol 2019; 23(02): 203-208
DOI: 10.1055/s-0038-1675392
Original Research
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Acoustic Voice Modifications in Individuals with Parkinson Disease Submitted to Deep Brain Stimulation

Aline Juliane Romann
1  Postgraduate program in Medicine: Medical sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
,
Bárbara Costa Beber
2  Phonoaudiology Department, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil
,
Carla Aparecida Cielo
3  Phonoaudiology Department, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil
,
1  Postgraduate program in Medicine: Medical sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
2  Phonoaudiology Department, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil
4  Neurology Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil
› Author Affiliations
Further Information

Publication History

27 March 2018

02 September 2018

Publication Date:
01 March 2019 (eFirst)

  

Abstract

Introduction Subthalamic nucleus deep brain stimulation (STN-DBS) improves motor function in individuals with Parkinson disease (PD). The evidence about the effects of STN-DBS on the voice is still inconclusive.

Objective To verify the effect of STN-DBS on the voice of Brazilian individuals with PD.

Methods Sixteen participants were evaluated on the Unified Parkinson Disease Rating Scale—Part III, and by the measurement of the acoustic modifications in on and off conditions of stimulation.

Results The motor symptoms showed significant improvement with STN-DBS on. Regarding the acoustic measures of the voice, only the maximum fundamental frequency (fhi) showed a statistical difference between on- and off-conditions, with reduction in off-condition.

Conclusion Changes in computerized acoustic measures are more valuable when interpreted in conjunction with changes in other measures. The single finding in fhi suggests that DBS-STN increases vocal instability. The interpretation of this result should be done carefully, since it may not be of great value if other measures that also indicate instability are not significantly different.