Abstract
Experimental studies showed that central polydactyly, syndactyly, and cleft hand might
appear when the same teratogenic factor acts on embryos at the same developmental
stage. These observations and some clinical cases support the concept that a common
etiologic mechanism is involved in the development of these malformations. We report
a clinical case that demonstrates the association previously observed in experimental
studies. Here, a patient with unilateral nonsyndromic cleft hand, central polydactyly,
first web syndactyly, osseous syndactyly between the ring and long fingers, and minor
thumb hypoplasia was presented.
Keywords
central polydactyly - cleft hand - syndactyly