Z Gastroenterol 2018; 56(08): e389-e390
DOI: 10.1055/s-0038-1669164
Kurzvorträge
Klinische Praxis und Versorgungsforschung
Perioperative Medizin/Versorgungsforschung/Outcome – Donnerstag, 13. September 2018, 08:00 – 09:36, 21a
Georg Thieme Verlag KG Stuttgart · New York

The role of saline irrigation prior to wound closure in the reduction of surgical site infection. A systematic review and meta-analysis. Systematic Review Registration: PROSPERO: CRD42018082287

P Ambe
1   Marien Hospital Düsseldorf, Klinik für Viszeral-, Minimal-invasive und Onkologische Chirurgie, Düsseldorf, Deutschland
2   Helios Universitätsklinikum Wuppertal, Universität Witten Herdecke, Lehrstuhl für Chirurgie II, Wuppertal, Deutschland
,
K Zarras
3   Marien Hospital Düsseldorf, Klinik für Viszeral-, Minimal-invasive und Ontologische Chirurgie, Düsseldorf, Deutschland
,
D Pieper
4   Institute for Research in Operative Medicine, Chair of Surgical Research, Witten/Herdecke University, Köln, Deutschland
,
T Rombe
4   Institute for Research in Operative Medicine, Chair of Surgical Research, Witten/Herdecke University, Köln, Deutschland
,
J Dörner
2   Helios Universitätsklinikum Wuppertal, Universität Witten Herdecke, Lehrstuhl für Chirurgie II, Wuppertal, Deutschland
,
JD Rembe
2   Helios Universitätsklinikum Wuppertal, Universität Witten Herdecke, Lehrstuhl für Chirurgie II, Wuppertal, Deutschland
,
H Zirngibl
2   Helios Universitätsklinikum Wuppertal, Universität Witten Herdecke, Lehrstuhl für Chirurgie II, Wuppertal, Deutschland
› Author Affiliations
Further Information

Publication History

Publication Date:
13 August 2018 (online)

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Background:

Surgical site infection describes an infectious complication of surgical wounds. This single complication is thought to occur in close to 20% of surgical cases. This complication has been described in all kinds of surgical procedure including minimally invasive procedures. Wound irrigation is frequently used as a means of reducing surgical site infection. However, there is lack of solid evidence to support routine wound irrigation. The aim of this review is provide evidence for the efficacy of routine wound irrigation with normal saline in preventing surgical site infection. The rate of surgical site infection in cases with and without wound irrigation will be analyzed.

Methods/Design:

Systematic literature searches will be conducted to identify all published and unpublished studies. The following databases will be searched for citations from inception to present: MEDLINE (via PubMed), EMBASE (via EMBASE), and CENTRAL (via the Cochrane library). The search strategy will be developed by the research team in collaboration with an experienced librarian and checked by a referee according to the Peer Review of Electronic Search Strategies (PRESS) guideline. A draft of the PubMed search strategy could be: (irrigation[tiab] OR „Therapeutic Irrigation“[mesh] OR lavage[tiab]) AND (saline[tiab] OR „Sodium Chloride“[mesh] OR sodium chloride[tiab]) NOT („Comment“ [Publication Type] OR „Letter“ [Publication Type] OR „Editorial“ [Publication Type]). No time limits will be set. The reference lists of eligible articles will be hand searched.

Results:

Relevant data will be extracted from eligible studies using a previously designed data extraction sheet. Relative risks will be calculated for binary outcomes and mean differences or standardized mean differences, if necessary, for continuous outcomes. For all measures 95% confidence levels will be calculated. Both arms would be compared with regard to the rate of surgical site infection within 30 days following surgery. We will report the review using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement.

Discussion:

This review aims at investigating the value of routine wound irrigation using normal saline in preventing surgical site infection.