Abstract
The progression of basal ganglia germ cell tumor (BGGCT) is slow and insidious, and
the diagnosis is often delayed. We report here an 11-year-old boy with BGGCT associated
with psychomotor deterioration and excessive salivation. Serial salivary gland scintigraphy
and single photon emission computed tomography suggested that the dysregulation of
basal ganglia to cortical circuitry accounts for the neurological comorbidity associated
with BGGCT. We also found that topical scopolamine patches are safe and effective
to suppress excessive salivation.
Clinical Trial Registration: No.
Keywords
basal ganglia germ cell tumor - excessive salivation - unstimulated salivary gland
scintigraphy - basal ganglia to cortical circuitry