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J Neurol Surg B Skull Base 2019; 80(01): 046-050
DOI: 10.1055/s-0038-1666851
Original Article
Georg Thieme Verlag KG Stuttgart · New York

Revascularization of AlloDerm Used during Endoscopic Skull Base Surgery

Zahrah M. Taufique
1   Department of Otolaryngology – Head and Neck Surgery, NYU Langone Medical Center, New York, United States
,
Nupur Bhatt
1   Department of Otolaryngology – Head and Neck Surgery, NYU Langone Medical Center, New York, United States
,
David Zagzag
2   Department of Pathology and Neurosurgery, NYU Langone Medical Center, New York, United States
,
Richard A. Lebowitz
1   Department of Otolaryngology – Head and Neck Surgery, NYU Langone Medical Center, New York, United States
,
Seth M. Lieberman
1   Department of Otolaryngology – Head and Neck Surgery, NYU Langone Medical Center, New York, United States
› Author Affiliations
Further Information

Publication History

19 February 2018

28 May 2018

Publication Date:
06 July 2018 (online)

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Abstract

Objectives AlloDerm is an acellular dermal matrix often used for reconstruction throughout the body. AlloDerm has been shown to undergo revascularization when used to reconstruct soft tissue such as in abdominal wall reconstruction. In this study, the authors review the literature on revascularization of AlloDerm and demonstrate the histologic findings of AlloDerm after implantation during skull base reconstruction.

Study Design Literature review and case reports.

Setting Tertiary Care Institution

Participants Patients from a tertiary care institution

Main Outcome Measures Histologic slides are evaluated and compared with nonimplanted AlloDerm.

Methods The authors review a case of explanted AlloDerm that had been used for skull base reconstruction after endoscopic skull base surgery.

Results Upon reviewing the histologic slides of explanted AlloDerm to nonimplanted AlloDerm, we demonstrate revascularization of AlloDerm when used in skull base reconstruction. Representative slides will be included.

Conclusions AlloDerm undergoes revascularization when used for skull base reconstruction.

Keywords

AlloDerm - skull base surgery - skull base reconstruction - acellular dermal matrix - revascularization
 

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