Thromb Haemost 1986; 55(02): 279-281
DOI: 10.1055/s-0038-1661537
Original Article
Schattauer GmbH Stuttgart

Identification of t-PA as the Major Active Plasminogen Activator in Human Milk

J M Marshall
The Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford, UK
,
M C P Rees
The Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford, UK
,
S A Cederholm-Williams
The Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford, UK
› Author Affiliations
Further Information

Publication History

Received 26 November 1985

Accepted 21 February 1986

Publication Date:
18 July 2018 (online)

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Summary

Human colostrum and milk contain high levels of plasminogen activator when compared with blood. These levels are inversely related to the duration of lactation and the activity appears to be due to tissue type plasminogen activator present in multiple (65-190 Kd) molecular weight forms.