Thromb Haemost 1985; 53(02): 252-254
DOI: 10.1055/s-0038-1661287
Original Article
Schattauer GmbH Stuttgart

Influence of Cyproheptadine on Endotoxin-Induced Disseminated Intravascular Coagulation (DIC) in Weaned Pigs

G Nowak
The Institute of Pharmacology and Toxicology, Medical Academy Erfurt, Erfurt, GDR
,
F Markwardt
The Institute of Pharmacology and Toxicology, Medical Academy Erfurt, Erfurt, GDR
› Author Affiliations
Further Information

Publication History

Received 02 March 1984

Accepted 04 February 1985

Publication Date:
18 July 2018 (online)

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Summary

Changes in the coagulation system typical of consumption reaction, microthrombosis in the lungs and other organs and haemodynamic disturbances caused by infusion of endotoxin in weaned pigs were prevented by treatment with the serotonin receptor antagonist cyproheptadine.