Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00035024.xml
Thromb Haemost 1984; 52(03): 224-225
DOI: 10.1055/s-0038-1661182
DOI: 10.1055/s-0038-1661182
Original Article
Examination of Certain Coagulation Factors in Menstrual Fluid from Women with Normal Blood Loss
Further Information
Publication History
Received 16 May 1984
Accepted 26 July 1984
Publication Date:
19 July 2018 (online)

Summary
Examination of coagulation factors in menstrual fluid collected from women with normal menstrual blood less (<80 ml) showed the absence of thrombin generating enzymes. Factor X, prothrombin and free thrombin were absent from menstrual fluid. No difference was found between days 1 and 2 of menstruation. Thus activation of coagulation enzymes occurs during normal menstruation though the menstrual blood is characteristically fluid.
-
References
- 1 Quick AJ. Menstruation in hereditary bleeding disorders. Obstet Gynecol 1966; 28: 37-48
- 2 Nilsson L, Rybo G. Treatment of menorrhagia with an antifibrinolytic agent, tranexamic acid (AMCA). Acta Obstet Gynecol Scand 1967; 46: 572-580
- 3 Skipetrov VP. The role of tissue factors of the endometrium in noncoagulability of the uterine blood. Exerpta Medica 1966; 10: 764
- 4 Rybo G. Plasminogen activators in the endometrium. Acta Obstet Gynecol Scand 1966; 45: 429-450
- 5 Hahn L, Rybo G. Fibrinogen-fibrin degradation products in menstrual blood from women with normal and excessive menstrual blood losses. Acta Obstet Gynecol Scand 1975; 54: 119-127
- 6 Beller FK. Observations on the clotting of menstrual blood and clot formation. Am J Obstet Gynaecol 1971; 3: 535-546
- 7 Christiaens GC M L, Sixma JJ, Haspels AA. Fibrin and platelets in menstrual discharge before and after the insertion of an intrauterine device. Am J Obstet Gynecol 1981; 140: 793-798
- 8 Sheppard BL, Dockeray CJ, Bonnar J. An ultrastructural study of menstrual blood in normal menstruation and dysfunctional uterine bleeding. Br J Obstet Gynaecol 1983; 90: 259-265
- 9 Christiaens GC M L, Sixma JJ, Haspels AA. Morphology of haemostasis in menstrual endometrium. Br J Obstet Gynaecol 1981; 87: 425-439
- 10 Lijnen HR, Collen D, Verstraete M. Synthetic substrates in clinical blood coagulation assays. Developments in Haematology. Martinus Nijhoff Publishers; The Hague: 1980. 1 1-114
- 11 Hallberg L, Hogdahl AM, Nilsson L, Rybo G. Menstrual blood loss - a population study. Acta Obstet Gynecol Scand 1966; 45: 320-351
- 12 Hallberg L, Nilsson L. Determination of menstrual blood loss. Scand J Clin Lab Invest 1964; 16: 244-248
- 13 Cederholm-Williams SA. Automated assay of antithrombins. Annal Clin Biochem 1980; 17: 183-184
- 14 Mancini G, Carbonara AO, Heremans JF. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry 1965; 2: 235-240
- 15 Starkey PM. α-2-macroglobulin: a review. In: Collen D, Wiman B, Verstraete M. (Eds) The physiological inhibitors of coagulation of fibrinolysis. Elsevier/North Holland; Amsterdam: 1979. pp l-11