Thromb Haemost 1985; 54(04): 901
DOI: 10.1055/s-0038-1660163
Letter to the Editor
Schattauer GmbH Stuttgart

Dihomo-γ-Linolenic Acid in Patients with Atherosclerosis: Effects on Platelet Aggregation, Plasma Lipids and Low-Density Lipoprotein-Induced Inhibition of Prostacyclin Generation

D P Mikhailidis
Department of Chemical Pathology and Human Metabolism, Royal Free Hospital and School of Medicine, London NW3 2QG, UK
,
M A Barradas
Department of Chemical Pathology and Human Metabolism, Royal Free Hospital and School of Medicine, London NW3 2QG, UK
,
P Dandona
Department of Chemical Pathology and Human Metabolism, Royal Free Hospital and School of Medicine, London NW3 2QG, UK
› Author Affiliations
Further Information

Publication History

Received 03 December 1984

Accepted 16 September 1985

Publication Date:
19 July 2018 (online)

 
  • References

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  • 2 Mikhailidis DP, Kirtland SJ, Barradas MA, Dandona P. Dihomogammalinolenic acid inhibits platelet aggregation and stimulates platelet prostaglandin production in healthy subjects: absence ofeffects in insulin-dependent diabetics. Diabetologia 1984; 27: 311A
  • 3 Hutton RA, Mikhailidis DP, Bernstein RM, Jeremy JY, Hughes GR V, Dandona P. Assessment of platelet functionin patients with Raynaud’s syndrome. J Clin Pathol 1983; 37: 182-187
  • 4 Mikhailidis DP, Mikhailidis AM, Barradas MA, Dandona P. Effect of nonesterified fatty acids on the stability of prostacyclin activity. Metabolism 1983; 32: 717-721
  • 5 Brox JH, Nordoy A. The effect of polyunsaturated fatty acids on endothelial cells andtheir production of prostacyclin, thromboxane and platelet inhibitory activity. Thromb Haemostas 1983; 50: 762-767
  • 6 Dandona P, Lomeo F, Khokher MA, Houlder S. Dihomogammalinolenic acid (DHLA) and linolenic acid potentiate thestimulatory effect of insulin and adipocyte lipogenesis. Diabetes 1983; 32 (Suppl. 01) 60A