Factor V Leiden Mutation in Women with Idiopathic Pulmonary Embolism

• References

• 1 Dahlbäck B. Resistance to activated protein C caused by the factor V R⁵⁰⁶Q mutation is a common risk factor for venous thrombosis. Thromb Haemost 1997; 78: 483-488
• 2 Desmarais S, de Moerloose P, Reber G, Minazio P, Perrier A, Bounameaux H. Resistance to activated protein C in an unselected population of patients with pulmonary embolism. Lancet 1996; 347: 1374-1375
• 3 Martinelli I, Cattaneo M, Panzeri D, Mannucci PM. Low prevalence of factor V: 506 in 41 patients with isolated pulmonary embolism. Thromb Haemost 1997; 77: 440-3
• 4 Manten B, Westendorp RGJ, Koster T, Reitsma PH, Rosendaal FR. Risk factor profiles in patients with different clinical manifestations of venous thromboembolism: a focus on the factor V Leiden mutation. Thromb Haemost 1996; 76: 510-513
• 5 Lane DA, Mannucci PM, Bauer KA, Bertina RM, Bochkov NP, Boulyjenkov V, Chandy M, Dahlbäck B, Ginter EK, Miletich JP, Rosendaal FR, Seligsohn U. Inherited thrombophilia: Part 1. Thromb Haemost 1996; 76: 651-662
• 6 Leroy-Matheron C, Levent M, Pignon J-M, Mendonça C, Gouault-Heilmann M. The 1691 G → A mutation in the factor V Gene: Relationship to activated protein C (APC) resistance and thrombosis in 65 patients. Thromb Haemost 1996; 75: 04-10
• 7 Heeb J, Kojima Y, Greengard JS, Griffin JH. Activated protein C resistance: molecular mechanisms based on studies using purified Gln⁵⁰⁶-factor V. Blood 1995; 85: 3405-3411
• 8 Rosing J, Tans G. Coagulation factor V: An old star shines again. Thromb Haemost 1997; 78: 427-433