Clot Component Reacting with Thrombin^[*]

Summary

The fibrin clot induced by a minimum amount of thrombin contains two components: one which forms the fibrin polymer spontaneously and another which does not form the polymer except in the presence of thrombin. The latter component produces non-protein nitrogen like fibrinogen itself, when reacting with thrombin. It is reasonable to conclude that the fissile component of the clot is an intermediate product of the fibrin formation.

^* Presented in part on the 6th Congress of the Polish Society of Hematology in Katowice, June 23—24, 1961.

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