Thromb Haemost 1962; 08(02): 270-275
DOI: 10.1055/s-0038-1655426
Originalarbeiten – Original Articles – Travaux Originaux
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Molecular Weights of Factor VIII (AHF) and Factor IX (PTC) by Electron Irradiation

David L Aronson
1   Department of Health, Education and Welfare, Public Health Service, National Institutes of Health Division of Biologics Standards, Bethesda 14, Maryland
,
John W Preiss*
1   Department of Health, Education and Welfare, Public Health Service, National Institutes of Health Division of Biologics Standards, Bethesda 14, Maryland
,
Michael W Mosesson
1   Department of Health, Education and Welfare, Public Health Service, National Institutes of Health Division of Biologics Standards, Bethesda 14, Maryland
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Publikationsdatum:
14. Mai 2019 (online)

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Summary

The molecular weights of AHF (factor VIII) and of PTC (factor IX) have been estimated by their sensitivity to inactivation by 7 kilovolt electrons. The molecular weight of AHF was found to be 180 000 by this method and that of PTC was found to be 110 000.

* National Institute of Arthritis and Metabolic Diseases.


** Pentex Inc., Kankakee, Ill.