The Hemostatic Effect of Adona (AC-17)

Chr. F Borchgrevink; Ragna Fölling Elgjo; K Hattel; P. F Hjort

doi:10.1055/s-0038-1655399

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1962; 07(03): 499-506
DOI: 10.1055/s-0038-1655399

Originalarbeiten — Original Articles — Travaux Originaux

Schattauer GmbH

The Hemostatic Effect of Adona (AC-17)

Authors

Chr. F Borchgrevink

¹Institute for Thrombosis Research, University Hospital, Rikshospitalet, Oslo, Norway (Head: Prof. P. A. Owren) and Vår Frues Hospital, Oslo, Norway (Head: Dr. R. Andersen)
Ragna Fölling Elgjo

¹Institute for Thrombosis Research, University Hospital, Rikshospitalet, Oslo, Norway (Head: Prof. P. A. Owren) and Vår Frues Hospital, Oslo, Norway (Head: Dr. R. Andersen)
K Hattel

¹Institute for Thrombosis Research, University Hospital, Rikshospitalet, Oslo, Norway (Head: Prof. P. A. Owren) and Vår Frues Hospital, Oslo, Norway (Head: Dr. R. Andersen)
P. F Hjort

¹Institute for Thrombosis Research, University Hospital, Rikshospitalet, Oslo, Norway (Head: Prof. P. A. Owren) and Vår Frues Hospital, Oslo, Norway (Head: Dr. R. Andersen)

Abstract

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Summary

In normal individuals 50 mg Adona (AC-17) intravenously increased capillary resistance, and slightly shortened the bleeding time. No effect was observed on coagulation or platelets.

In patients undergoing prostatic surgery the drug seemed to reduce the blood loss during the operation.

50 mg Adona (AC-17) was given to 11 patients with a prolonged bleeding time of various causes, and to 8 patients with a positive tourniquet test. No effect could be demonstrated. However, the drug may be of value in some patients with acquired, ill-defined, presumably vascular diseases.

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References

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