Thromb Haemost 1963; 10(01): 146-150
DOI: 10.1055/s-0038-1654770
Originalarbeiten — Original Article — Travaux Originaux
Schattauer GmbH

The Effect of Aminopterin Sodium on Plasma Fibrinogen, Antifibrinolysin and Euglobulin Lysis Time[*]

Authors

  • J Frederic Johnson

    1   Department of Physiology and Pharmacology, Wayne State University College of Medicine, Detroit, Michigan, USA
  • Rashid A Zeineh

    1   Department of Physiology and Pharmacology, Wayne State University College of Medicine, Detroit, Michigan, USA
Further Information

Publication History

Publication Date:
22 June 2018 (online)

Summary

The daily oral administration of Aminopterin Sodium to normal dogs was accompanied by an increase in plasma antifibrinolysin concentration, an increase in plasma fibrinogen concentration and a decrease in euglobulin fibrinolytic activity.

* This investigation was supported by a research grant HE-05141 from the National Heart Institute, National Institute of Health, U.S. Public Health Service.