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Thromb Haemost 1961; 6(02): 308-316
DOI: 10.1055/s-0038-1654563
Originalarbeiten — Original Articles — Travaux Originaux
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The Investigation of a Patient with an Unusual Coagulation Defect

Emiliano L. Gomes
1   “Socorro Doenças do Sangue”, 5a Cad. Clin. Med., Fac. Nac. Med., Rio de Janeiro, Brazil Blood Coagulation Research Unit, Churchill Hospital, Oxford
,
Therezinha R. Calicchio
1   “Socorro Doenças do Sangue”, 5a Cad. Clin. Med., Fac. Nac. Med., Rio de Janeiro, Brazil Blood Coagulation Research Unit, Churchill Hospital, Oxford
,
Rosemary Biggs
1   “Socorro Doenças do Sangue”, 5a Cad. Clin. Med., Fac. Nac. Med., Rio de Janeiro, Brazil Blood Coagulation Research Unit, Churchill Hospital, Oxford
› Author Affiliations
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Publication History

Publication Date:
12 July 2018 (online)

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Summary

1. The coagulation defect of a patient whose blood contains an inhibitor is described.

2. The inhibitor lengthens the clotting time of plasma in the presence of weak thromboplastin and also interferes with the mechanism of glass contact activation.

3. It is suggested that the inhibitor is similar to those which occur in the blood of patients with disseminated lupus erythematosus.

 

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