Thrombosis and Haemostasis, Table of Contents Thromb Haemost 1961; 6(01): 157-159DOI: 10.1055/s-0038-1654548 Originalarbeiten — Original Articles — Travaux Originaux Schattauer GmbH Inhibition of Fibrinoid Deposition by Heparin Saul B. Gilson M.D. 1 Department of Pathology, Jewish Memorial Hospital, New York City› Author AffiliationsRecommend Article Abstract Buy Article Conclusion Experimental glomerulitis in rabbits following intravenous injection of gamma globulin was inhibited by heparinization. The physiological and patho-physiological significance of this observation is considered. Full Text References References (1) Movat H. Z. The concept of fibrinoid. Amer. J. med. Sei. 236: 373-382 1958; (2) Gitlin D, Craig J. M, Janeway C. A. Variations in the staining characteristics of human fibrin. Amer. J. Path. 33: 267-283 1957; (3) Good R. A, Thomas L. Studies on generalized Shwartzman reaction; prevention of local and generalized Shwartzman reactions with heparin. Bull. Johns Hopk. Hosp. 97: 871-888 1953; (4) Kleinerman J. Effects of heparin on experimental nephritis in rabbits. Lab. Invest. 3: 495-508 1954; (5) Rosenman R. H, Solomon B, Byers S. O, Friedman M. Arresting effect of heparin upon experimental nephrosis in rats. Proc. Soc. exp. Biol. (N. Y.) 86: 599-603 1954; (6) Hawn C. V. Z, Janeway C. A. Histological and serological sequences in experimental hypersensitivity. J. exp. Med. 571-590 1947; (7) Abrahams D. G, Glynn L. E. Heparin tolerance in rheumatic fever. Clin. Sei. 8: 171-180 1949; (8) Shapiro S. S, McKay D. G. The prevention of the generalized Shwartzman reaction with sodium warfarin. J. exp. Med. 107: 377-381 1958; (9) Robbins J, Stetson C. A. An effect of antigen-antibody interaction on blood coagulation. J. exp. Med. 109: 1-8 1959; (10) Mellors R. C, Ortega L. G. Analytical pathology: new observations on pathogenesis of glomerulonephritis, lipid nephrosis, periarteritis nodosa, and secondary amyloidosis in man. Amer. J. Path. 32: 455-499 1956;
