Thrombosis and Haemostasis, Table of Contents Thromb Haemost 1960; 4(02): 244-252DOI: 10.1055/s-0038-1654502 Originalarbeiten — Original Articles — Travaux Originaux Schattauer GmbH Improvements in the Thrombin Generation Test Preben Ollendorff 1 Biological Institute of the Carlsberg Foundation, Copenhagen, and the Old Peoples Towny Copenhagen, Denmark› Author AffiliationsRecommend Article Abstract Buy Article Summary The influence of glass contact on the thrombin generation test was demonstrated and a modified method described. Nearly all prothrombin had been converted to thrombin before the thrombin concentration reached its maximum. Full Text References References (1) Astrup Tage, Müllertz S. The Fibrin Plate Method for Estimating Fibrinolytic Activity. Arch. Biodiem. Biophys. 40: 346 1952; (2) Astrup Tage, Sjølin Knud-Erik. Defects in Blood Coagulation. Dan med Bull 4: 164-168 1957; (3) Biggs Rosemary, Douglas A. S, Macfarlane R. G. The Initial Stages of Blood Coagulation. J. Physiol. 122: 538-553 1953; (4) Dybkær René. A Coagulometer” for the Thrombin Generation Test on Plasma. Thromb. Diath. haem. 3: 110-112 1959; (5) Dybkær René, Geill Torben. The Thrombin Generation Test on Plasma. Methods and Variation. Acta haemat. (Basel) 21: 156-165 1959; (6) Geill Torben. Studies on Blood Coagulation in Old Age. Pulmonary Thrombosis and Embolism. in: Cirrhosis of the Liver. Experimentelle Alternsforschung, Symposium Basel, IV 4.—7. 1956. 267-269 Birkhäuser; Basel, Stuttgart: 1956 (7) Geill Torben. Studier over blodkoagulationen i seniet. Forekomst af lungeemboli og thrombose. Nord. Med. 58: 1586-1587 1957; (8) Geill Torben. Studies on Blood Coagulation in Old. Age. Thrombin Formation Following Haematomas and Traumatic Injuries to the Tissue. Fourth Congress of the Int. Assoc, of Geront., Merano (Bolzano), Italy. July 14—19, 1957. 357-361 Merano: 1957 (9) Kesseler Karlheinz. Über die klinische Bedeutung des Thrombin-Bildungstests. Dtsdi med. Wschr. 84: 267-272 1959; (10) Macfarlane R. G, Biggs Rosemary. A Thrombin Generation Test. The Application in Haemophilia and Thrombocytopenia. J. clin. Pathol. 6: 3-8 1953; (11) Margolis J. Glass Surface and Blood Coagulation. Nature 178: 805-806 1956; (12) O’Brien J. R. Relation of Blood-Coagulation to Lipaemia. Lancet 269: 690-693 1955; (13) Ollendorff Preben. Defects in and Variability of the Thromboplastic System in Horse Plasma. Thromb. Diath. haem.. 1959 In the press. (14) Owren P. A, Aas K. The Control of Dicumarol Therapy and the Quantitative Determination of Prothrombin and Proconvertin. Scand. J. clin. Lab. Invest 3: 201-208 1951; (15) Pitney W. R. Mild Haemophilia — a Clinical and Laboratory Study. Aust Ann Med. 6: 44-52 1957; (16) Pitney W. R, Dacie J. V. A Simple Method of Studying the Generation of Thrombin in Recalcified Plasma. Application in the Investigation of Haemophilia. J. clin Pathol. 6: 9-14 1953; (17) Poole J. C. F, Robinson D. S. Further Observations on the Effects of Ethanolamine Phosphatide on Plasma Coagulation. Quart. J. exp. Physiol 41: 295-300 1956; (18) Quick Armand J, Epstein Ernst. Thromboplastic Activity in Human Blood. J. appi. Physiol. 4: 840-847 1952; (19) Quick Armand J, Hussey Clara V, Epstein Ernst. Activation of Thromboplastin by Thrombin. Amer. J. Physiol. 174: 123-126 1953; (20) Robinson D. S, Poole J. C. F. The Similar Effect of Chylomicra and Ethanolamine Phosphatide on the Generation of Thrombin During Coagulation. Quart. J. exp. Physiol. 41: 36-50 1956; (21) Sjølin Knud-Erik. The Thrombin Generation Test in the Diagnosis of Classical Hemophilia and Christmas Disease. Scand. J. clin. Lab. Invest. 8: 138-144 1956; (22) Sjølin Knud-Erik. Deficiency of a Factor in the Plasma Thromboplastin System revealed by Freezing. Dan. med. Bull. 3: 222-223 1956; (23) Sjølin Knud-Erik. Lack of Christmas Factor in Horse Plasma. Nature 178: 153 1956; (24) Sjølin Knud-Erik. Deficiency of the Hageman Factor Demonstrated by the Thrombin Generation Test. Thromb. Diath. haem. 1: 153-157 1957; (25) Sjølin Knud-Erik. The Hageman Trait in a Family with Haemorrhagic Diathesis. Acta genet. (Basel) 7: 541-548 1957; (26) Sjølin Knud-Erik. Coagulation Defect in Horse Plasma. Proc. Soc. exp. Biol. (N. Y.) 94: 818-820 1957; (27) Sjølin Knud-Erik. Variations of the Coagulation Defect in Hemophilia. VII Congresso Della Societa Internationale Di Ematologia. Roma: 1958: 287. (28) Sjølin Knud-Erik. Hemophilic Diseases in Denmark. Thesis. 1959 In the press. (29) Waaler Bjarne A. Contact Activation in the Intrinsic Blood Clotting System. Scand. J. clin. Lab. Invest.. 11. Suppl, no. 37 1959
