The Influence of Blood Corpuscles on Clot Firmness: Thrombelastographic Observations

Summary

Red and white corpuscles cause a reduction in maximal amplitude values of thrombelastographic tracings. This is due to an inhibition of clot firmness. In this work the quantitative relation between maximal amplitude reduction and cell volume was proved experimentally. It was also investigated how blood cells cause the observed modifications in t.e.graphic tracings.

• References

• (1) Budtz-Olsen O. E. Clot retraction. Blackwell Scientific Publications; Oxford: 1951
• (2) Della Santa R, Duraffourd P. Ber. Int. Kongr. Thrombose u. Embolie. Basel: 1954
• (3) Hartert H. Die Thrombelastographie. Eine Methode zur physikalischen Analyse des Blutgerinnungsvorganges. Z. ges. exp. Med. 117: 189 1951;
• (4) Hörder M. H, Pileggi J. Beeinflussung der Haftfähigkeit des Thrombus durch Leukozyten der chronisch leukämischen Myelose. Acta haemat. (Basel) 17: 111 1957;
• (5) Marmont A, Palmieri A, Giacca S. Suile modificazioni quantitative provocate dalla somministrazione endovenosa di eparina sulla piastrinemia capillare e venosa delPuomo. Atti del 1° Simposio sui problemi attinenti alla Coagulazione dei sangue. Genova: dicembre 1953: 428.
• (6) Tocantins L. M. The coagulation of blood. Methods of Study. Gruñe & Stratton. 1955: 155.
• (7) Vulpis N, De Matteis F. Attività trombelastografica del siero immune antipiastrine. Policlinico, Sez. med. 65: 269 1958;
• (8) Ware A. G, Guest M. M, Seegers W. H. Fibrinogen: With Special Reference to its Preparation and Certain Properties of its Products. Arch. Biochem. 13: 231 1947;
• (9) Weiner M, Weisberg L. G. Clot firmness. Blood 12: 1125 1957;
• (10) Winckelmann G, Hörder M. H. Veränderung der Gerinnselhaftfähigkeit durch Leukozyten der myeloischen Reihe. Thrombelastographische Untersuchungen bei chronischen myeloischen Leukämien, akuten Urämien und reaktiven Leukozytosen. Acta haemat. (Basel) 18: 261 1957;