“Angiokinase” - Molecular Weights of Proteins Representing a Perivascular Plasminogen Activator

W Auerswald; B Binder; W Doleschel

doi:10.1055/s-0038-1653691

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1971; 26(02): 411-413
DOI: 10.1055/s-0038-1653691

Vorläufige Mitteilungen – Preliminary Reports – Communications Préliminaires

Schattauer GmbH

“Angiokinase” - Molecular Weights of Proteins Representing a Perivascular Plasminogen Activator

W Auerswald

¹Department of Physiology (Director: Prof. Dr. W. Auerswald), School of Medicine, University of Vienna, Austria

,

B Binder

¹Department of Physiology (Director: Prof. Dr. W. Auerswald), School of Medicine, University of Vienna, Austria

,

W Doleschel

¹Department of Physiology (Director: Prof. Dr. W. Auerswald), School of Medicine, University of Vienna, Austria

› Author Affiliations

Abstract

Summary

By means of gel filtration (Sephadex G-150) of precipitates originating from human cadaver vessel perfusates the molecular weights of a perivascular plasminogen activator “angiokinase” were determined. Maximum angiokinase activity was found at the molecular weight 61,000, high activities at 30,500 and 120,000, and traces of activity at 15,000, 45,700, and 76,000. Presumably angiokinase is the product of polymerization of a basic unit (mol. weight 30,500) or its subunit (mol. weight 15,000).

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References

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