Thromb Haemost 1969; 21(01): 304-310
DOI: 10.1055/s-0038-1653539
Originalarbeiten - Original Articles - Travaux Originaux
Schattauer GmbH

Enhancement of Fibrinolysis by Venous Occlusion Results of Long-Term Thrombelastography and Activator Determination

F Holzknecht
1  Department of Internal Medicine (Head: Prof. H. Braunsteiner, University of Innsbruck, Austria
,
F Spöttl
1  Department of Internal Medicine (Head: Prof. H. Braunsteiner, University of Innsbruck, Austria
,
H Braunsteiner
1  Department of Internal Medicine (Head: Prof. H. Braunsteiner, University of Innsbruck, Austria
› Author Affiliations
The technical assistance of Miss Annemarie Hiesmayr and Miss Edeltraud Obrist is gratefully acknowledged.
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Publication History

Publication Date:
10 June 2018 (online)

Summary

Global fibrinolysis and activator activity were investigated in venous blood before and after occlusion. Global fibrinolysis was determinated by thrombelastography with a low speed of the paper drive (longterm thrombelastography). The fibrinolysis on the thrombelastographic curves were evaluated by the slant (a°) of the inflectional tangent at the thrombelastographic branch.

A considerable increase of global fibrinolytic activity and also of the activator activity after venous congestion was found. There was a slight correlation between the global fibrinolysis and the activator before occlusion and a strong correlation after congestion. There was, however, no accordance between the regression lines of the two correlations. Other factors of activation of fibrinolysis may be involved.