Thromb Haemost 1969; 21(01): 217-222
DOI: 10.1055/s-0038-1653530
Originalarbeiten - Original Articles - Travaux Originaux
Schattauer GmbH

Studies on Tissue Thromboplastin - Its Splitting into Two Separable Parts

M Hvatum
1  The Department of Microbiology, Dental Faculty, University of Oslo, Blindern, Norway
,
H Prydz
1  The Department of Microbiology, Dental Faculty, University of Oslo, Blindern, Norway
› Institutsangaben
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Publikationsverlauf

Publikationsdatum:
10. Juni 2018 (online)

Summary

1. Sodium deoxycholate (DOC) splits tissue thromboplastin into two inactive parts, fraction A and fraction B, separable by gel filtration in the presence of DOC.

2. By recombination and subsequent removal of the DOC, the fractions reaggregate and regain full thromboplastic activity.

3. Fraction A consists mainly of protein, while phospholipid is the main constituent of fraction B.