Thromb Haemost 1969; 21(01): 159-165
DOI: 10.1055/s-0038-1653521
Originalarbeiten - Original Articles - Travaux Originaux
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Effect of Phlogodym on Tourniquet Shock

G Lázár
1  Institute of Pathophysiology (Director: Prof. Dr. S. Karády) and Institute of Anatomy (Director: Prof. Dr. A. Gellért), University of Szeged School of Medicine, Szeged, Hungary
,
S Karády
1  Institute of Pathophysiology (Director: Prof. Dr. S. Karády) and Institute of Anatomy (Director: Prof. Dr. A. Gellért), University of Szeged School of Medicine, Szeged, Hungary
,
E Husztik
1  Institute of Pathophysiology (Director: Prof. Dr. S. Karády) and Institute of Anatomy (Director: Prof. Dr. A. Gellért), University of Szeged School of Medicine, Szeged, Hungary
› Author Affiliations
Further Information

Publication History

Publication Date:
10 June 2018 (online)

Summary

Our experiments revealed that Phlogodym had a marked adverse effect on the sublethal tourniquet shock of rats. This effect was associated with a simultaneous drop in fibrinogen levels and platelet counts. In the hind limbs of the animals treated with Phlogodym and submitted to tourniquet, a thrombo-hemorrhagic phenomenon which macroscopically and microscopically resembled the Shwartzman Reaction, developed 5 to 20 hrs after the removal of the tourniquet.