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Thromb Haemost 1977; 38(03): 0652-0659
DOI: 10.1055/s-0038-1651880
DOI: 10.1055/s-0038-1651880
Original Article
Megakaryocytes in the Giant Platelet Syndrome
A Cytochemical and Ultrastructural StudyAuthors
Weitere Informationen
Publikationsverlauf
Received
15. Dezember 1976
Accepted
14. Juni 1977
Publikationsdatum:
04. Juli 2018 (online)
Summary
When compared to normal megakaryocytes, those from a patient with the giant platelet syndrome exhibited numerous cytochemical abnormalities. These reflected disturbances in the metabolism of RNA, glycogen, arginine-rich histone, and various glycolytic enzymes. Ultrastructural studies of the abnormal megakaryocytes also showed decreased glycogen and RNA (ribosomes) as well as aberrations of nuclear lobulation.
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