Molecular Biology of Human Plasminogen

 

^* Presented at the Postgraduate Course and Workshop “Progress in Fibrinolysis”, Milan, March 6-8, 1975.

• References

• 1 Abiko Y, Iwamoto M, Tomikawa M. 1969; Plasminogen-plasmin system. V. A stoichiometric equilibrium complex of plasminogen and a synthetic inhibitor. Biochimica Biophysica Acta 185: 424.
• 2 Alkjaersig N. 1964; The purification and properties of human plasminogen. Biochemical Journal 93: 171.
• 3 Bang Jr. W. F, Boggiano E, and De Renzo E. C. 1965; Starch-gel electrophoretic analysis of highly purified human plasminogen. Biochimica Biophysica Acta 104: 470.
• 4 Brockway W. J, and Castellino F. J. 1972; Measurement of the binding of antifibrino-lytic amino acids to various plasminogens. Archives Biochemistry Biophysics 151: 194.
• 5 Castellino F. J, Siekring Jr. G. E, Sodetz J. M, and Bretthauer R. K. 1973; Amino terminal amino acid sequences and carbohydrate of the two major forms of rabbit plasminogen. Biochemical Biophysical Research Communications 53: 845.
• 6 Claeys H, Molla A, and Verstraete M. 1973; Conversion of NH₂-terminal glutamic acid to NH₂-terminal lysine human plasminogen by plasmin. Thrombosis Research 3: 515.
• 7 Claeys H, and Vermylen J. 1974; Physico-chemical and proenzyme properties of NH a-terminal glutamic acid and NH₂-terminal lysine plasminogen. Influence of 6-aminohexanoic acid. Biochimica Biophysica Acta 342: 351.
• 8 Collen D, Ong E. B, and Johnson A. J. 1972; a Native human plasminogen (Abstract). Federation Proceedings 31 (02) 229.
• 9 Collen D, Tytgat G, Claeys H, Verstraete M, and Wallen P. 1972; b Metabolism of plasminogen in healthy subjects: effect of tranexamic acid. Journal Clinical Investigation 51: 1310.
• 10 Collen D. 1973 a The microheterogeneity of human plasminogen. Doctorate Thesis, Faculty of Sciences, University of Leuven.
• 11 Collen D. 1973 b Plasminogen turnover studies in man. IV Congress International Society Thrombosis Haemostasis, Vienna, Abstract volume, p. 118.
• 12 Collen D. 1974 Plasminogen and prothrombin metabolism in man. Thesis, University of Leuven, Belgium.
• 13 Deutsch D. G, and Mertz E. T. 1970; Plasminogen: purification from human plasma by affinity chromatography. Science 170: 1095.
• 14 Groskopf W. R, Summaria L, and Robbins K. C. 1969; Studies on the active center of human plasmin. Partial amino acid sequence of a peptide containing the active center serine residue. Journal Biological Chemistry 244: 3590.
• 15 Hatton M. W. and Regoeczi 1974; Some observations on the affinity chromatography of rabbit plasminogen. Biochimica Biophysica Acta 359: 55.
• 16 Liu T. H, and Mertz E. T. 1971; Studies on plasminogen. IX. Purification of human plasminogen from Cohn fraction III by affinity chromatography. Canadian Journal Biochemistry 49: 1055.
• 17 Muramatu M, Hayakumo Y, Onishi T, Sato T, and Fujii S. 1969; Comparison. of human plasmins formed by activation with trace and large amounts of streptokinase. Journal Biochemistry (Japan) 65: 329.
• 18 Rickli E. E, and Cuendet P. A. 1971; Isolation of plasmin-free human plasminogen with N-terminal glutamic acid. Biochimica Biophysica Acta 250: 447.
• 19 Rickli E. E, and Otavsky W. I. 1973; Release of an N-terminal peptide from human plasminogen during activation with urokinase. Biochimica Biophysica Acta 295: 381.
• 20 Robbins K. C, Summaria L, Elwyn D, and Barlow G. H. 1965; Further studies on the purification and characterization of human plasminogen and plasmin. Journal Biological Chemistry 240: 541.
• 21 Robbins K. C, Summaria L, Hsieh B, and Shah B. J. 1967; The peptide chains of human plasmin; mechanism of activation of human plasminogen to plasmin. Journal Biological Chemistry 242: 2333.
• 22 Robbins K. C, and Summaria L. 1970. Human plasminogen and plasmin. In: Pearl-man G. E, and Lorand L. (ed.) Methods in Enzymology, vol. XIX: Proteolytic Enzymes. Academic Press; New York: 184.
• 23 Robbins K. C, Bernabe P, Arzadon L, and Summaria L. 1972; The primary structure of human plasminogen 1. The NH₂-terminal sequence of human plasminogen and the #-carboxymethyl heavy (A) and light (B) chain derivatives of plasmin. Journal Biological Chemistry 247: 6757.
• 24 Robbins K. C, Bernabe P, Arzadon L, and Summaria L. 1973; a The primary structure of human plasminogen. II. The histidine loop of human plasmin: light (B) chain active center histidine sequence. Journal Biological Chemistry 248: 1631.
• 25 Robbins K. C, Bernabe P, Arzadon L, and Summaria L. 1973; b NH₂-terminal sequences of mammalian plasminogens and plasmin S-carboxymethyl heavy (A) and light (B) chain derivatives of plasminogen. Journal Biological Chemistry 248: 7242.
• 26 Siefring Jr. G. E, and Castellino F. J. 1974; The role of sialic acid in the determination of distinct properties of isoenzymes of rabbit plasminogen. Journal Biological Chemistry 249: 7742.
• 27 Sjoholm I, Wiman B, and Wallen P. 1973; Studies on the conformational changes of plasminogen induced during activation to plasmin and by 6-amino-hexanoic acid. European Journal Biochemistry 39: 471.
• 28 Sodetz J. M, Brockway W. J, and Castellino F. J. 1972; Multiplicity of rabbit plasminogen. Physical characterization. Biochemistry 11: 4451.
• 29 Summaria L, Arzadon L, Bernabe P, and Bobbins K. C. 1972; Studies on the isolation of the multiple molecular forms of human plasminogen and plasmin by isoelectric focusing methods. Journal Biological Chemistry 247: 4691.
• 30 Summaria L, Arzadon L, Bernabe P, and Bobbins K. C. 1973; Characterization of the NH₂-terminal glutamic acid and NH₂-terminal lysine forms of human plasminogen isolated by affinity chromatography and isoelectric focusing methods. Journal Biological Chemistry 248: 2984.
• 31 Walther P. J, Steinman H. M, Hill R. L, and McKee P. A. 1974; Activation of human plasminogen by urokinase; partial characterization of a preactivation peptide. Journal Biological Chemist 249: 1173.
• 32 Wallen P. B. 1962; Studies on the purification of human plasminogen. II. Further purification of human plasminogen on cellulose ion exchangers and by means of gel filtration on Sephadex. Arkiv Kemi 19: 469.
• 33 Wallen P, and Wiman B. 1970; Characterization of human plasminogen. I. On the relationship between different molecular forms of plasminogen demonstrated in plasma and found in purified preparations. Biochimica Biophysica Acta 221: 20.
• 34 Wallen P, and Wiman B. 1972; Characterization of human plasminogen. II. Separation and partial characterization of different molecular forms of human plasminogen. Biochimica Biophysica Acta 257: 122.
• 35 Wiman B. 1973; Primary structure of peptides released during activation of human plasminogen by urokinase. European Journal Biochemistry 39: 1.
• 36 Wiman B, and Wallen P. 1973; Activation of human plasminogen by an insoluble derivative of urokinase ; structural changes of plasminogen in the course of activation to plasmin and demonstration of a possible intermediate compound. European Journal Biochemistry 36: 25.