Thromb Haemost 1969; 22(02): 344-350
DOI: 10.1055/s-0038-1651360
Originalarbeiten-Original Articles-Travaux Originaux
Schattauer GmbH

Studies with the Chandler Rotating Loop

Evidence that Thrombin Generation is Responsible for the Formation of the Artificial in Vitro Thrombi
H Engelberg M. D.
1   Cedars-Sinai Medical Research Institute and the Division of Medicine, Cedars-Sinai Medical Center, Los Angeles, California
› Author Affiliations
Supported by the Council for Tobacco Research.
Further Information

Publication History

Publication Date:
10 June 2018 (online)

Summary

Evidence has been presented that thrombin formation and coagulation are the major processes involved in the formation of the clot-thrombus when blood is rotated in the Chandler loop, and that platelet aggregation is secondary to thrombin formation. It is suggested that the test be called the flowing clotting time or the clot-thrombus formation time.

 
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