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Thromb Haemost 1981; 45(01): 006-011
DOI: 10.1055/s-0038-1650119
Original Article
Schattauer GmbH Stuttgart

Determining Survivals of Platelets and Fibrinogen Using HAP an Interactive Hemostasis Analysis Computer Program

Mark J Abramson
The Department of Chemistry, and School of Medicine, Emory University, U.S.A
,
Sidney F Stein
The Department of Chemistry, and School of Medicine, Emory University, U.S.A
,
J H Goldstein
The Department of Chemistry, and School of Medicine, Emory University, U.S.A
› Author Affiliations
Further Information

Publication History

Received 28 April 1980

Accepted 28 October 1980

Publication Date:
04 July 2018 (online)

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Summary

An interactive computer program is described which permits computation of platelet survivals based on the gamma function model of Murphy. An additional feature permits the treatment of other labelled proteins, e. g. fibrinogen, disappearing via an exponential process. The program requires no prior computer background and typical determinations of survivals can be effected in about five min, representing a substantial enhancement to the gamma function program as currently provided by the International Committee for the Standardization of Hematology. Provision has also been made for modifications to meet individual needs. The program is described in sufficient detail, including sample calculations, to permit evaluation for possible applications.

Keywords

Platelet survival - Fibrinogen survival - Computer program - Automated
 

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