Thromb Haemost 1980; 43(03): 194-197
DOI: 10.1055/s-0038-1650050
Original Article
Schattauer GmbH Stuttgart

An Attempt at Predicting Postoperative Deep Vein Thrombosis by Preoperative Coagulation Studies in Patients Undergoing Total Hip Replacement

Dennis W T Nilsen
The Oslo Emergency Medical Centre, University Hospital of Ullevål, Oslo and State Laboratory of Microbiology, Department of Immunohaematology and Blood Transfusion, Lillehammer, Norway
,
Miladin Jeremic
The Oslo Emergency Medical Centre, University Hospital of Ullevål, Oslo and State Laboratory of Microbiology, Department of Immunohaematology and Blood Transfusion, Lillehammer, Norway
,
Odd K Weisert
The Oslo Emergency Medical Centre, University Hospital of Ullevål, Oslo and State Laboratory of Microbiology, Department of Immunohaematology and Blood Transfusion, Lillehammer, Norway
› Author Affiliations
Further Information

Publication History

Received 20 March 1980

Accepted 21 May 1980

Publication Date:
13 July 2018 (online)

Summary

Preoperative levels of fibrinogen, factors V, VII, VIII and antithrombin III were measured in 25 consecutive patients undergoing total hip replacement. Deep vein thrombosis (D.V.T.) was detected by fibrinogen-uptake test in 60% of the patients. The preoperative fibrinogen level was significantly higher (p < 0.05), and serum antithrombin III was markedly lower (p ≦ 0.1) in patients with postoperative D.V.T. The quotient of fibrinogen to serum antithrombin III was significantly higher (p < 0.01) in patients with D.V.T. This quotient may serve as an additional parameter to other clinical and laboratory tests in prediction of postoperative D.V.T. following hip surgery.