Thromb Haemost 1980; 43(03): 192-193
DOI: 10.1055/s-0038-1650049
Original Article
Schattauer GmbH Stuttgart

Gel Permeation Chromatography of Heparins

Barbara Mulloy
The National Institute for Biological Standards and Control, Holly Hill, Hampstead, London, England
,
Edward A Johnson
The National Institute for Biological Standards and Control, Holly Hill, Hampstead, London, England
› Author Affiliations
Further Information

Publication History

Received 16 April 1980

Accepted 16 May 1980

Publication Date:
13 July 2018 (online)

Summary

Gel permeation chromatography of heparins using water as solvent has recently been used to obtain fractions for biological investigation. We find that heparin fractions obtained in this way are not, necessarily, differentiated simply on a molecular size basis as has been alleged. Correlations between biological activity and molecular size obtained using such fractions must therefore be treated with caution.