Comparison of Real-Time B-Mode Ultrasonography and Doppler Ultrasound with Contrast Venography in the Diagnosis of Venous Thrombosis in Symptomatic Outpatients

Alberto Cogo; Anthonie W A Lensing; Paolo Prandoni; Harry R Büller; Antonio Girolami; Jan Wouter ten Cate

doi:10.1055/s-0038-1649594

Thrombosis and Haemostasis, Inhaltsverzeichnis

Thromb Haemost 1993; 70(03): 404-407
DOI: 10.1055/s-0038-1649594

Original Article

Clinical Studies

Schattauer GmbH Stuttgart

Comparison of Real-Time B-Mode Ultrasonography and Doppler Ultrasound with Contrast Venography in the Diagnosis of Venous Thrombosis in Symptomatic Outpatients

Alberto Cogo

¹The Institute of Medical Semeiotics, Department of Patologia Medica II, University of Padua, Padua, Italy

,

Anthonie W A Lensing

²The Center for Thrombosis, Haemostasis, Atherosclerosis and Inflammation Research, Academic Medical Centre, Amsterdam, The Netherlands

,

Paolo Prandoni

¹The Institute of Medical Semeiotics, Department of Patologia Medica II, University of Padua, Padua, Italy

,

Harry R Büller

²The Center for Thrombosis, Haemostasis, Atherosclerosis and Inflammation Research, Academic Medical Centre, Amsterdam, The Netherlands

,

Antonio Girolami

¹The Institute of Medical Semeiotics, Department of Patologia Medica II, University of Padua, Padua, Italy

,

Jan Wouter ten Cate

²The Center for Thrombosis, Haemostasis, Atherosclerosis and Inflammation Research, Academic Medical Centre, Amsterdam, The Netherlands

› Institutsangaben

Abstract

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Summary

In a prospective study, we compared real-time B-mode ultrasonography, using the simple criteria of common femoral and popliteal vein compressibility (Compression US), and Doppler ultrasound, using a standardized technique (Doppler US), with contrast venography in 158 consecutive outpatients symptomatic for deep-vein thrombosis of the lower limbs (DVT). For proximal vein thrombosis, the sensitivities documented for Compression US and Doppler US were 100% (95% CI: 90% to 100%) and 89% (95% CI: 76% to 96%), respectively. This difference is not statistically significant (p = 0.056). For all thrombi (including isolated calf-vein thrombosis), however, the sensitivity of Compression US was significantly higher than that of Doppler US (95% and 76%, respectively; p <0.04). Compression US was normal in all patients with normal venogram (specificity, 100%; 95% CI: 95% to 100%), while Doppler US was abnormal in two patients with normal venogram (specificity, 98%; 95% CI: 92% to 100%). The specificities of the two tests did not differ significantly. The results of our comparison suggest that Compression US is superior to Doppler US in the detection of DVT in symptomatic outpatients.

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Referenzen

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