A Serial Micro-Fibrinolysis Test and Its Use in Rats with Liver-Bypass^[*]

Summary

A micro-euglobulin lysis test is described for serial testing in individual rats. With the method it was shown that the rat a) responds well with a fibrinolytic reaction to carbachol, b) that a liver-bypass in this animal produces a sustained fibrinolytic reaction which c) after subsiding can be re-established by carbachol and that d) the fibrinolytic phase in rats with liver-bypass lasts longer after preceding splenectomy and adrenalectomy.

^* This work was supported by grants from the American Heart Association and the National Heart Institute, U. S. Public Health Service (HE 5538 and 5 T1 — HE 5638).

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