Thromb Haemost 1977; 37(03): 477-483
DOI: 10.1055/s-0038-1649258
Original Article
Schattauer GmbH

Early Venous Thrombosis

A Scanning Electron Microscopic Study
T. K Day
1   From Kings College Hospital, Denmark Hill, London S. E. 5., England
,
S. V Cowper
1   From Kings College Hospital, Denmark Hill, London S. E. 5., England
,
V. V Kakkar
1   From Kings College Hospital, Denmark Hill, London S. E. 5., England
,
K. G. A Clark
1   From Kings College Hospital, Denmark Hill, London S. E. 5., England
› Author Affiliations
Further Information

Publication History

Received 10 January 1977

Accepted 22 February 1977

Publication Date:
03 July 2018 (online)

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Summary

The passage of a minimal electric charge was used to initiate thrombosis in rabbit femoral veins, and the events occurring during formation of the thrombus were observed using scanning electron microscopy. Thrombosis began to occur within ten minutes after passage of the charge, upon an apparently unaltered endothelium. The first event was the laying down of a fibrin meshwork and this was shortly followed by the appearance of regularly arranged platelet clumps.