Summary
Coagulation and fibrinolysis were evaluated in 29 healthy young male adults before,
immediately after and one hour after strenuous exercise on a treadmill. Seven subjects
were studied after moderate, prolonged exercise. Fourteen volunteers were tested before
and after successful physical conditioning. Measurements included: pulse rate, glass
and silicone whole blood clotting times, one-stage prothrombin time, Stypven time,
two-stage prothrombin time, prothrombin consumption, partial thromboplastin time,
thrombin time, fibrinogen, eugiobulin lysis time, antifibrinolysin, hematocrit, and
platelet count. Immediately after exercise, a marked increase in fibrinolytic activity
and an acceleration of most clotting assays were observed. After physical conditioning
there was a decrease in the level of fibrinolytic activity at rest and after exercise,
but the reactivity of the fibrinolytic system, i.e., the percent increase in fibrinolytic
activity in response to exercise, was unaltered. Following physical conditioning,
the clotting times of certain assays were less accelerated.
