CC-BY-NC-ND 4.0 · AJP Rep 2018; 08(02): e99-e105
DOI: 10.1055/s-0038-1648253
Case Report
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Early Pulmonary Interstitial Emphysema in Preterm Neonates—Respiratory Management and Case Report in Nonventilated Very Low Birth Weight Twins

Judith Gronbach
1  Department of General and Neonatology, Center for Pediatrics and Youth Medicine, Justus Liebig University of Giessen, Germany
,
Harald Ehrhardt
1  Department of General and Neonatology, Center for Pediatrics and Youth Medicine, Justus Liebig University of Giessen, Germany
2  German Lung Research Center (DZL), Giessen, Germany
,
Klaus-Peter Zimmer
1  Department of General and Neonatology, Center for Pediatrics and Youth Medicine, Justus Liebig University of Giessen, Germany
,
Markus Waitz
1  Department of General and Neonatology, Center for Pediatrics and Youth Medicine, Justus Liebig University of Giessen, Germany
› Author Affiliations
Funding Sources No external funding was secured for this article.
Further Information

Publication History

11 September 2017

20 March 2018

Publication Date:
14 May 2018 (online)

Abstract

Early pulmonary interstitial emphysema in extreme preterm neonates is closely linked with respiratory distress syndrome and exposure to mechanical ventilation. In severe cases, maintaining adequate gas exchange aiming to avoid further lung damage and other neonatal morbidities associated with systemic/pulmonary hypoperfusion, prolonged hypoxia, and respiratory acidosis can be challenging and requires in-depth knowledge into the pathophysiology of the disease. Herein, we report on very low birth weight twins who developed early pulmonary interstitial emphysema during noninvasive respiratory support. We further review the current evidence from the literature, specifically addressing on possible preventive measures and the respiratory management options of this acute pulmonary disease in high-risk neonates.

Financial Disclosures

The authors have nothing to disclose.