Inhibition by Ethanol of Thrombus Formation Induced by Indwelling Aortic Catheters in Rabbits

M L Rand; H M Groves; M A Packham; J F Mustard; R L Kinlough-Rathbone

doi:10.1055/s-0038-1648171

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1991; 65(04): 454-455
DOI: 10.1055/s-0038-1648171

Letter to the Editor

Schattauer GmbH Stuttgart

Inhibition by Ethanol of Thrombus Formation Induced by Indwelling Aortic Catheters in Rabbits

Authors

M L Rand

¹Department of Biochemistry, University of Toronto, Toronto, Ont., Canada, M5S 1A8
H M Groves

²Department of Biomedical Sciences, McMaster University, Hamilton, Ont., Canada, L8N 3Z5
M A Packham

¹Department of Biochemistry, University of Toronto, Toronto, Ont., Canada, M5S 1A8
J F Mustard

³Department of Pathology, McMaster University, Hamilton, Ont., Canada, L8N 3Z5
R L Kinlough-Rathbone

³Department of Pathology, McMaster University, Hamilton, Ont., Canada, L8N 3Z5

Abstract

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References

References
1 Owens CA, McIntire LV, Lasslo A. Ethanol inhibition of thrombus formation on collagen-coated glass. Thromb Haemostas 1990; 63: 510-516
2 Rand ML, Groves HM, Kinlough-Rathbone RL, Packham MA, Mustard JF. Effects of ethanol on rabbit platelet responses to collagen in vitro and ex vivo and on platelet adhesion to de-endothelialized aortae in vivo. Thromb Res 1987; 48: 379-388
3 Rand ML, Groves HM, Packham MA, Mustard JF, Kinlough-Rathbone RL. Experimentally-induced thrombus formation in rabbits is inhibited by ethanol. Faseb J 1990; 4: A1028
4 Rand ML, Groves HM, Packham MA, Mustard JF, Kinlough-Rathbone RL. Acute administration of ethanol to rabbits inhibits thrombus formation induced by indwelling aortic catheters. Lab Invest 1990; 63: 742-745
5 Groves HM, Kinlough-Rathbone RL, Richardson M, Moore S, Mustard JF. Platelet interaction with damaged rabbit aorta. Lab Invest 1979; 40: 194-200
6 Packham MA, Mustard JF. Platelet adhesion. In: Progress in Hemostasis and Thrombosis, vol 7 Spaet TH. (ed). Grune and Stratton; Orlando, FL: 1984. pp 211-288
7 Keller JW, Folts JD. Combined inhibitory effects of aspirin and ethanol on adrenaline exacerbation of acute platelet thrombus formation in stenosed canine coronary arteries. Cardiovasc Res 1990; 24: 191-197
8 Keller JW, Folts JD. Relative effects of cigarette smoke and ethanol on acute platelet thrombus formation in stenosed canine coronary arteries. Cardiovasc Res 1987; 22: 73-78
9 Lawrence JB, Bodenheimer SL, Kramer WS, Zekert SL. Clinically-relevant concentrations of ethanol inhibit platelet adherence on human arterial subendothelium and collagen-induced platelet aggregation. Blood 1989; 74: 402a
10 Rand ML, Packham MA, Kinlough-Rathbone RL, Mustard JF. Effects of ethanol on pathways of platelet aggregation in vitro. Thromb Haemostas 1988; 59: 383-387
11 Rand ML, Vickers JD, Kinlough-Rathbone RL, Packham MA, Mustard JF. Thrombin-induced inositol trisphosphate production by rabbit platelets is inhibited by ethanol. Biochem J 1988; 251: 279-284
12 Klatsky AL, Friedman GD, Siegelaub AB. Alcohol and mortality. A ten-year Kaiser-Permanate experience. Ann Intern Med 1981 95. 139-145
13 Marmot MG, Rose G, Shipley MJ, Thomas BJ. Alcohol and mortality: A U-shaped curve. Lancet 1981; i: 580-583
14 Gordon T, Kannel WB. Drinking and mortality. The Framingham study. Am J Epidemiol 1984 120. 97-107
15 Moore RD, Pearson TA. Moderate alcohol consumption and coronary artery disease. A review. Medicine 1986 65. 242-266
16 Friedman LA, Kimball AW. Coronary heart disease mortality and alcohol in Framingham. Am J Epidemiol 1986; 124: 481-489
17 Klatsky AL, Armstrong MA, Friedman GD. Alcohol and cardiovascular deaths. Circulation 1989; 80: 11-614