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CC BY-NC-ND 4.0 · Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery 2021; 40(03): e277-e279
DOI: 10.1055/s-0038-1646933
Case Report | Relato de Caso

Sarcoidosis Mimicking Skull Base Meningioma

Sarcoidose mimetizando meningioma na base do crânio
Jennyfer Paulla Galdino Chaves
1   Department of Neurosurgery, Hospital Cajuru, Curitiba, PR, Brazil
,
Carlos Alberto Mattozo
1   Department of Neurosurgery, Hospital Cajuru, Curitiba, PR, Brazil
,
Adriano Keijiro Maeda
1   Department of Neurosurgery, Hospital Cajuru, Curitiba, PR, Brazil
,
Luciane Filla
2   Department of Neurology, Hospital Cajuru, Curitiba, PR, Brazil
,
Aline Kelly de Cezaro Piva
2   Department of Neurology, Hospital Cajuru, Curitiba, PR, Brazil
,
Thiago Suzuki
2   Department of Neurology, Hospital Cajuru, Curitiba, PR, Brazil
,
Larissa Luvison Gomes da Silva
3   Department of Pathology, Hospital Cajuru, Curitiba, PR, Brazil
,
Alexandre Novicki Francisco
1   Department of Neurosurgery, Hospital Cajuru, Curitiba, PR, Brazil
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Abstract

Sarcoidosis is a systemic disease characterized by granulomatous inflammation. Pulmonary and lymphatic granulomatous involvement are common. We present a rare case report of involvement of the central nervous system affecting the ocular region and mimicking optic nerve sheath meningioma. We report the case of a 79-year-old female patient with progressive visual impairment with an evolution of 4 years. A magnetic resonance imaging scan of the cranium with gadolinium and intense homogeneous contrast enhancement revealed an expansive lesion in the right optic nerve, at the height of the optic canal. The patient was submitted to the neurosurgical approach with lesion biopsy, which showed sarcoidosis of the central nervous system. Due to the rarity of central nervous system involvement, the diagnosis of this pathology may unfortunately be postponed. The present article aims to elucidate this pathology as a differential diagnosis of retro-orbital tumors.

Resumo

Sarcoidose é uma doença sistêmica caracterizada por inflamação granulomatosa em que o envolvimento pulmonar e linfático é comum. Apresentamos um relato de caso raro de envolvimento do sistema nervoso central com acometimento ocular mimetizando meningioma da bainha do nervo óptico. Relatamos o caso de uma paciente de 79 anos, do sexo feminino, com diminuição visual progressiva com evolução de 4 anos. A ressonância magnética do crânio com gadolínio, mediante intenso realce homogêneo pelo meio de contraste, evidenciou uma lesão expansiva no nervo óptico direito, na altura do canal óptico. A paciente foi submetida a abordagem neurocirúrgica com biópsia de lesão, que evidenciou sarcoidose do sistema nervoso central. Devido à raridade do acometimento do sistema nervoso central, o diagnóstico dessa patologia pode ser, infelizmente, postergado. O presente artigo tem como objetivo elucidar a patologia como diagnóstico diferencial dos tumores retro-orbitários.

Keywords

sarcoidosis - ocular sarcoidosis

Palavras-Chave

sarcoidose - sarcoidose ocular


Publication History

Received: 13 November 2017

Accepted: 22 February 2017

Article published online:
24 April 2018

© 2018. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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