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Thromb Haemost 1978; 39(03): 707-711
DOI: 10.1055/s-0038-1646747
Original Article
Schattauer GmbH Stuttgart

Creatine Phosphate in Rat Blood Platelets

Sachiko Shibata
The Radioisotope Research Laboratory, School of Pharmaceutical Sciences, Kitasato University, Tokyo 108, Japan
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Publication History

Received 05 October 1977

Accepted 12 December 1977

Publication Date:
12 July 2018 (online)

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Summary

Creatine phosphate (CP) was found in rat platelets by an assay method devised to increase the specificity and sensitivity. In this method, radioactivity of [14 C] ATP was measured after the reaction of CP with [14 C]ADP in the presence of creatine kinase. The mean value of the CP content in rat platelets was 24.8 nmoles per 109 platelets. Since the molar ratio of CP and ATP was 1:2.6, it is probable that CP plays a role in the energy metabolism of rat platelets.

 

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