Purification of a Fibrinolysis Inhibitor in Serum from Post-Traumatic Patients^[*]

Summary

A fibrinolysis inhibitor was purified in serum from post-traumatic patients by the use of flat bed electrofocusing of serum desalted by gel chromatography followed by affinity chromatography on a column of matrix-linked plasminogen. Disc gel electrophoresis yielded one protein band. The inhibitor protein was also found in normal serum, but in a lower concentration.

^* This investigation was presented at the 8th Meeting of the Swedish Society for Forensic Medicine, Stockholm, November 29th, 1975. A brief report from this meeting has earlier been published (Forensic Science 7, 83, March 1976).

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