171 chronic arterial occlusions and 86 acute venous thromboses were treated by systemic
ultrahigh streptokinase (UHSK) infusions. 38% of the patients were over 65, 27% over
70 years of age. The UHSK scheme consisted of a 1.5 million units SK per hour maintenance
infusion over a period of 6 hours. 46% of the patients received one, 47% two, 6% three,
and 1% four series (one series per day). 81% of the arterial patients had a history
of less than 3 months. In 54% of the cases PTA followed UHSK treatment for dilation
of a residual stenosis or removal of occlusion residues still persistent. In the venous
patients the most proximal location was distributed as follows: calf veins 1%, femoral
vein 57%, iliac vein 28%, subclavian vein 14%. The average thrombosis history was
8 days.
Clearance rates of chronic arterial occlusions
By setting up of sub-groups more favorable results were calculated. For exemple, a
femoral occlusion group consisting of cases with a history shorter than 6 weeks and
2 or 3 calf arteries patent displayed a clearance rate of 77%, a figure much higher
than the overall femoral result
Clearance rates of deep venous thrombosis
The thrombosis duration played a significant role for thrombosis dissolution. The
average occlusion history was 6 days in the total clearance group compared with 12
days in the unsuccessful cohort.
