Gastrointestinal stromal tumors (GISTs) are rare in occurrence, but comprise the most
common mesenchymal tumors of the gastrointestinal tract and affect between 15 and
20 individuals per million per year. Due to recent advancements in molecular classification
of these tumors, medical therapy has provided improved outcomes to a historically
surgically managed disease. This review article briefly discusses the molecular characteristics,
medical and surgical therapies, and future of GIST management.
Keywords
gastrointestinal stromal tumors - mesenchymal tumors - GIST management