Abstract
Appendiceal neoplasms are identified in 0.9 to 1.4% of appendiceal specimens, and
the incidence is increasing. It has long been professed that neuroendocrine tumors
(formerly carcinoids) are the most common neoplastic process of the appendix; recent
data, however, has suggested a shift in epidemiology. Our intent is to distill the
complex into an algorithm, and, in doing so, enable the surgeon to seamlessly maneuver
through operative decisions, treatment strategies, and patient counseling. The algorithm
for evaluation and treatment is complex, often starts from the nonspecific presenting
complaint of appendicitis, and relies heavily on often subtle histopathologic differences.
Keywords
appendiceal neoplasms - gastrointestinal neuroendocrine tumors - appendiceal neuroendocrine
tumors - pseudomyxoma peritonei - adenoneuroendocrine carcinoma
