Semin intervent Radiol 2018; 35(02): 92-98
DOI: 10.1055/s-0038-1642036
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Epidemiology, Pathophysiology, and Natural History of Pulmonary Embolism

Meredith Turetz
Division of Pulmonary and Critical Care, Department of Medicine, Weill Cornell Medicine, New York, New York
,
Andrew T. Sideris
NYU School of Medicine, New York, New York
,
Oren A. Friedman
Cedars-Sinai Medical Center, Los Angeles, California
,
Nidhi Triphathi
Leon H Charney Division of Cardiology, Department of Medicine, NYU Langone Health, New York, New York
,
James M. Horowitz
Leon H Charney Division of Cardiology, Department of Medicine, NYU Langone Health, New York, New York
› Author Affiliations
Further Information

Publication History

Publication Date:
04 June 2018 (online)

Abstract

Pulmonary embolism (PE) is a common and potentially deadly form of venous thromboembolic disease. It is the third most common cause of cardiovascular death and is associated with multiple inherited and acquired risk factors as well as advanced age. The prognosis from PE depends on the degree of obstruction and hemodynamic effects of PE and understanding the pathophysiology helps in risk-stratifying patients and determining treatment. Though the natural history of thrombus is resolution, a subset of patients have chronic residual thrombus, contributing to the post-PE syndrome.