Vet Comp Orthop Traumatol 2018; 31(04): 304-310
DOI: 10.1055/s-0038-1635577
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Computed Tomography Findings of Pigmented Villonodular Synovitis in a Dog

Lara M. Dempsey
1  Institute of Veterinary Science, University of Liverpool, Wirral, United Kingdom of Great Britain and Northern Ireland
2  Department of Small Animal Surgery, Chestergates Veterinary Specialists, Cheshire, United Kingdom of Great Britain and Northern Ireland
,
Thomas W. Maddox
3  Institute of Veterinary Science, University of Liverpool plus Institute of Ageing and Chronic Disease, Liverpool, Cheshire, United Kingdom of Great Britain and Northern Ireland
,
Thelma Meiring
4  IDEXX Laboratories Ltd., Yorkshire, West Yorkshire, United Kingdom of Great Britain and Northern Ireland
,
Brandan Wustefeld-Janssens
5  Department of Small Animal Clinical Sciences, Texas A&M University, Texas, United States
,
Eithne J. Comerford
3  Institute of Veterinary Science, University of Liverpool plus Institute of Ageing and Chronic Disease, Liverpool, Cheshire, United Kingdom of Great Britain and Northern Ireland
› Author Affiliations
Further Information

Publication History

06 May 2017

20 February 2018

Publication Date:
04 June 2018 (eFirst)

Abstract

Pigmented villonodular synovitis (PVNS) is a rare benign and usually monoarticular neoplastic lesion arising from the synovium, bursae and tendon sheaths in humans, horses and dogs. Categorization for PVNS in humans includes localized and diffuse forms of PVNS and tenosynovial giant cell tumour (TGCT), although histologically they are the same. The localized form is characterized by discrete nodular lesions, the diffuse form is often intra-articular, infiltrative, affecting the entire synovium with more aggressive behaviour and TGCT occurs along tendon sheaths. Computed tomography (CT) of PVNS is well described in humans but not documented in the veterinary literature. Pigmented villonodular synovitis is not a straightforward diagnosis and CT is useful to further characterize radiographic findings. A representative open surgical biopsy of the synovium is essential to obtaining the diagnosis and ruling out malignancy. Currently, there are no guidelines for the diagnosis of PVNS in dogs or long-term follow-up of these cases. This case report describes the presentation, diagnostic findings, treatment and long-term outcome of a 4-year-old male Labrador Retriever with confirmed PVNS. Clinical outcome was considered fair with the dog's lameness and symptoms remaining stable with medical management 3 years following the initial diagnosis.

Author Contributions

Lara M. Dempsey, Thomas W. Maddox and Eithne J. Comerford contributed to conception of study, study design, acquisition of data, and data analysis and interpretation. Thelma Meiring contributed to acquisition of data, and data analysis and interpretation. Brandan Wustefeld-Janssens contributed to conception of study, acquisition of data, and data analysis and interpretation. All authors drafted and revised and approved the submitted manuscript.