Abstract
Vein of Galen aneurysmal malformation (VGAM) is a rare intracranial vascular anomaly
in the choroidal arteries characterized by the persistence of the embryonic median
prosencephalic vein of Markowski (MProsV). It is common in children with high mortality
and disability rates. VGAM-associated clinical presentations include heart failure,
hydrocephalus, and neurological symptoms, which make it difficult for diagnosis. Simultaneously,
the complex VGAM vascular architecture, characterized by a wide interindividual variability,
makes the management of this condition challenging to clinicians. Thus, timely diagnosis
and treatment of VGAM are crucial. In this review article, we elucidated the latest
research progresses of VGAM in the aspects of the pathogenesis, classification, clinical
features, imaging, management, and prognosis based on recent relevant literatures.
It is beneficial to raise the awareness of VGAM and improve the level of management
and treatment.
Keywords
vein of Galen aneurysmal malformation - vein of Galen - review
