The Influence of the Dietary Protein Content on Growth in Giant Breed Dogs
Received for publication:
21 October 1992
06 February 2018 (online)
Feeding immature dogs of large breeds a diet exceeding the NRC recommendations (5) for energy, protein, calcium (Ca), phosphorus (P), and vitamin D may result in disturbances of skeletal development. The effects of excess energy and various Ca:P ratios per se have been reported. The role of dietary protein, especially with regard to skeletal growth in giantbreed dogs was studied. Clinical, biochemical, radiographical, and histological parameters were studied in three groups of Great Dane pups raised on diets only differing in protein content (14.6, 23.1 and 31.6% dm respectively). Significant differences were found for body weight, plasma albumin, and plasma urea. The differences in protein intake per se had no demonstrable consequences for renal and skeletal development. A causative role for dietary protein in disturbed enchondral ossification in dogs is unlikely.
Nutrition is important during growth, especially in giant breed dogs. The role of dietary protein with regard to skeletal development was studied in three groups of Great Dane pups raised on diets only differing in protein content. A causative role for dietary protein in disturbed enchondral ossification is unlikely.
- 1 Brinker WO, Piermattei DL, Flo GL. Osteochondrosis. In: Handbook of Small Animal Orthopedics and Fracture Treatment. Philadelphia: Saunders; 1990: 305-11.
- 2 Olsson SE. Morphology and physiology of the growth plate cartilage under normal and pathologic conditions. In: Bone in Clinical Orthopaedics. Sumner-Smith G. (ed.) Philadelphia: Saunders; 1982: 159-96.
- 3 Lenchan TM, VanSickle DC. Canine osteochondrosis. In: Textbook of Small Animal Orthopaedics. Newton CD, Nunamaker DM. (eds). Philadelphia: Saunders; 1985: 981-95.
- 4 Hcdhammer A, Wu F, Krook L. et al. Overnutrition and skeletal disease: An experimental study in growing Great Dane dogs. Cornell Vet 1974; 64 (05) 1-160.
- 5 National Research Council.. Nutrient Requirements of Dogs, National Academy of Science. Washington: National Academy Press; 1974
- 6 Lavelle RB. The effects of the overfeeding of a balanced complete commercial diet to a group of growing Great Danes. In: Nutrition of the Dog and Cat. Burger IH, Rivers JPW. (eds). Cambridge: Cambrige University Press; 1989: 303-15.
- 7 Hazewinkel HAW, Goedegebuure SA, Poulos PW. et al. Influences of chronic calcium excess on the skeletal development of growing Great Danes. J Am Anim Hosp Assoc 1985; 21: 377-91.
- 8 Strombcrg B, Rcjno S. Osteochondrosis in the horse. I. A clinical and radiologic investigation of osteochondrosis dissecans of the knee and hock joint. Acta Radiol 1978; Suppl. 358: 139-52.
- 9 Reiland S, Strombcrg B, Olsson S-E. et al. Osteochondrosis in growing bulls. Acta Radiol 1978; Suppl. 358: 179-96.
- 10 Grondalen T. Leg weakness in pigs. I. Incidence and relationship to skeletal lesions, feed level, protein and mineral supply, exercise and exterior conformation. Acta Vet Scand 1974; 15: 555-73.
- 11 Poulos PW, Reiland S, Elwinger K. et al. Skeletal lesions in the broiler, with special reference to dyschondroplasia (osteochondrosis). Acta Radiol 1978; Suppl. 358: 197-227.
- 12 Center SA. Pathophysiology and laboratory diagnosis of liver disease. In: Textbook of Veterinary Internal Medicine. Philadelphia: Saunders; 1989: 1421-78.
- 13 Van Wyk JJ, Underwood LE. Normal and aberrant growth. In: Williams Textbook of Endocrinology. Wilson JD, Foster DW. (eds). Philadelphia: Saunders; 1992: 1079-138.
- 14 Kopple JD. Role of diets in the progression of chronic renal failure: Experience with human studies and proposed mechanisms by which nutrients may retard progression. J Nutr 1991; 121: S124.
- 15 Bovee KC, Kronfeld DS, Ramberg C. et al. Long-term measurement of renal function in partially nephrectomized dogs. Invest Urol 1979; 16: 378-84.
- 16 Bovee KC. Influence of dietary protein on renal function in dogs. J Nutr 1991; 121: S128-39.
- 17 Klahr S. Effects of protein intake on the progression of renal disease. Ann Rev Nutr 1989; 9: 87-108.
- 18 Polzin DJ, Leininger JR, Osborne CA. et al. Development of renal lesions in dogs after 11/12 reduction of renal mass: Influences of dietary protein intake. Lab Invest 1988; 58: 172-83.
- 19 Nap RC, Hazewinkel HAW, Voorhout F. et al. Growth and skeletal development in Great Dane pups fed different levels of protein intake. J Nutr 1991; 121: S107-S13.
- 20 Voorhout G, Hazewinkel HAW. Radiographic studies of the skeletal development in Great Danes on different calcium in-takes. Vet Radiol 1987; 28: 152-7.
- 21 Brom WE, van den Biewenga WJ. Assessment of glomerular filtration rate in normal dogs: analysis of the MCr-EDTA clearance and its relation to several endogenous parameters of glomerular filtration. Res Vet Sci 1981; 30: 152-7.
- 22 Goedegebuure SA, Hazewinkel HAW. Morphological findings in young dogs chronically fed a diet containing excess calcium. Vet Pathol 1986; 23: 594-605.
- 23 Hazewinkel HAW, van den Brom WE, van’t Klooster ATh. et al. Calcium metabolism in Great Dane dogs fed diets with various calcium and phosphorus levels. J Nutr 1991; 121: S99-S106.
- 24 National Research Council.. Nutrient Requirements of Dogs, National Academy of Science. Washington: National Academy Press; 1985
- 25 Ontko JA, Wuthier RE, Phillips PH. The effect of increased dietary fat upon the protein requirement of the growing dog. J Nutr 1957; 62: 163-9.
- 26 Schaeffer MC, Rogers QR, Morris JG. Protein in the nutrition of dogs and cats. In: Nutrition of the Dog and Cat. Burger IH, Rivers JPW. (eds). Cambridge: Cambridge University Press; 1989: 159-205.
- 27 Rivers JPW, Burger IH. The current consensus in dogs and cat nutrition. In: Nutrition of the Dog and Cat. Burger IH, Rivers JPW. (eds). Cambridge: Cambridge University Press; 1989: 7-9.
- 28 Case LP, Czarnecki-Maulden GL. Protein requirements of growing pups fed practical dry-type diets containing mixed-protein sources. Am J Vet Res 1990; 51: 808-12.
- 29 Meyer H. Energie und Niihrstoffc - Stoffwechsel und Bedarf. In: Ernahrung des Hundes. Stuttgart: Ulmer; 1990: 67-125.
- 30 Sheffy BE. Meeting energy-protein needs of dogs. Comp Cont Educ Pract Vet 1979; 1: 345-54.
- 31 Sheffy BE. The 1985 revision of the National Research Council nutrient requirements of dogs and its impact on the petfood industry. In: Nutrition of the Dog and Cat. Burger IH, Rivers JPW. (eds). Cambridge: Cambridge University Press; 1989: 11-26.
- 32 Wheech AA, Gocttsch E, Reeves EB. Nutritional edema in the dog. I. Development of hypoprotcinemia on a diet deficient in protein. J Exp Med 1935; 61: 299-317.
- 33 Lewis LD, Morris ML, Hand MS. Prepared dog foods. In: Small Animal Clinical Nutrition III. Topcka: Mark Morris Associates; 1989: A2.1-A2.8.
- 34 Hostetter TH, Meyer TW, Rennke HG. et al. Chronic effects of dietary protein in the rat with intact and reduced renal mass. Kidney Int 1986; 30: 509-17.
- 35 Romsos DR, Belo PS, Bennink MR. et al. Effect of dietary carbohydrate, fat and protein on growth, body composition and blood metabolite levels in the dog. J Nutr 1976; 106: 1452-64.